Advances in Consumer Research
Issue 3 : 125-148
Original Article
Stability Indicating Analytical Method Development And Validation For The Determination Of Favipiravir By Rp-Hplc
 ,
 ,
 ,
 ,
 ,
 ,
1
Associate Professor, Department of Pharmaceutical Analysis, VJ’s College of Pharmacy, Rajamahendravaram, Andhra Pradesh
2
Department of Pharmaceutical Analysis, VJ’s College of Pharmacy, Rajamahendravaram, Andhra Pradesh Student.
3
Student, Department of Pharmaceutical Analysis, VJ’s College of Pharmacy, Rajamahendravaram, Andhra Pradesh.
Abstract

A simple, Precised, Accurate method was developed for the determination of Favipiravir  by RP-HPLC technique. Chromatographic conditions used are stationary phase Agilent c18 150 x 4.6 mm, 5m. Mobile phase 0.1% OPA buffer: Acetonitrile in the ratio of 50:50 and flow rate was maintained at 1ml/min, detection wave length was 230 nm, column temperature was set to 30oC and diluent was Acetonitrile: Water (50:50), Conditions were finalized as optimized method. System suitability parameters were studied by injecting the standard five times and results were well under the acceptance criteria. Linearity study was carried out between 25% to150 % levels, R2 value was found to be as 0.999. Precision was found to be 0.7% for repeatability and 1.2% for intermediate precision. LOD and LOQ are 1.140µg/ml and 4.424µg/ml respectively. By using above method assay of marketed formulation was carried out 100.37% was present. The above method can be used in routine quality control analysis.

 

Keywords
Recommended Articles
Original Article
Spatial Integration Modeling for the Development of Blue Economy–Based Aquaculture Investment in Central Sulawesi Province
...
Original Article
Examining the Drivers of Cryptocurrency Addiction – A Study with Special Reference to Indian Gen Z
...
Original Article
“Effect of AI-Based Customer Service has on Customer Satisfaction and Loyalty as Applied to Quick Commerce”
...
Original Article
Navigating Marketing Challenges and Policy Support: A Study of Tech Start-ups in Odisha
Loading Image...
Volume 3, Issue 3
Citations
967 Views
565 Downloads
Share this article
© Copyright Advances in Consumer Research